Il continuo monitoraggio del virus SARS-CoV-2 e delle sue varianti, tramite unica PCR, è lo strumento più efficace nelle mani dei sistemi sanitari mondiali per mantenere sotto controllo il virus responsabile della CoViD-19 ed intercettare sul nascere nuovi focolai. ...

Months after the first SARS-CoV-2 variant has been sequenced, many scientific works have largely hypothesized the clinical impact of the mutations, based on in silico experiments. Starting point The role of SARS-CoV-2 mutations has been supposed to impact the immune...

All Sars-CoV-2 Variants of Concern (VOC) such as B.1.1.7 (aka UK) or B.1.351 (aka South African) harbor typical and own patterns of mutations, also out of the Spike glycoprotein. B.1.1.7 contains 21 among missense mutations and deletions which 9 within Spike gene (del...

Months ahead of forced coexistence with Sars-CoV-2, when we thought we knew the virus intimately and profoundly by hundreds of scientific works and hundreds of miles of sequencing reads, here the variants made their appearance. Nothing new, nothing unexpected. Brand...

  Several SARS-CoV-2 variants of concern (VOC) have emerged. To be able to confirm infection with a specific variant, sequencing of the whole SARS-CoV-2 genome, or at least whole or partial S-gene for the current variants is required. While countries are building...

One of the main concerns related to the pandemic response politics is the spread of SARS-CoV-2 variants. This is not only related to epidemiological researches but may impact the virus ability to spread among people and to escape the immune system response. Starting...